APTX CLIA Kit for Dog(Canis familiaris) | EIAab.comAPTX CLIA Kit for Dog(Canis familiaris)

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Index > Protein center > APTX(Gene name) > Dog

APTX (Gene name),

Aprataxin (Protein name ), APTX_CANFA from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

APTX;

Protein name:

Aprataxin;

Alternative:

Forkhead-associated domain histidine triad-like protein(FHA-HIT);

Organism:

Dog (Canis familiarisCanis lupus familiaris).

General Annotation

Sub Unit:

Interacts with single-strand break repair proteins XRCC1, XRCC4, ADPRT and p53/TP53. Interacts with NCL. Interacts (via FHA-like domain) with MDC1 (phosphorylated).

Function:

DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

Subcellular Location:

Nucleus nucleoplasm Nucleus nucleolus Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage. Colocalizes with MDC1 at sites of DNA double-strand breaks. Interaction with NCL is required for nucleolar localization.

Protein Attributes:

Sequence length:

342

Sequence:

50:

100:

150:

200:

250:

300:

342:

GRVSVRDGMP | ELLKLPLRCH | ECQQLLPSIP | QLKEHLRRHW | PK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Cfa.113

KEGG:

cfa:442943

STRING:

9615.ENSCAFP00000002638

String:

P61797

Uniprot:

P61797

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ELISA Kit for Dog Aprataxin

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E9623p

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ELISA Kit for Dog Aprataxin

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E9623d

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ELISA Kit for Dog Aprataxin

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E9623h

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ELISA Kit for Dog Aprataxin

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E9623r

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ELISA Kit for Dog Aprataxin

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E9623m

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ELISA Kit for Dog Aprataxin

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E9623b

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ELISA Kit for Dog Aprataxin

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E9623c

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96T

CLIA Kit for Dog Aprataxin

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U9623d

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96T

CLIA Kit for Dog Aprataxin

Cat.:

U9623m

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96T

CLIA Kit for Dog Aprataxin

Cat.:

U9623b

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96T

CLIA Kit for Dog Aprataxin

Cat.:

U9623r

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96T

CLIA Kit for Dog Aprataxin

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U9623c

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96T

CLIA Kit for Dog Aprataxin

Cat.:

U9623p

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96T

CLIA Kit for Dog Aprataxin

Cat.:

U9623h

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96T

Polyclonal Antibody for Dog Aprataxin

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P9623Rb-h

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40ug/0.2ml

Polyclonal Antibody for Dog Aprataxin

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P9623Rb-r

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40ug/0.2ml

Polyclonal Antibody for Dog Aprataxin

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P9623Rb-m

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Monoclonal Antibody for Dog Aprataxin

Protein for Dog Aprataxin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of human FHA-HIT gene homolog in dog."
Chen Y. , Huang C.-H.
Submitted (2002-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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